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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > LY-2857785CAS：1619903-54-6
Molecular Formula：C26H36N6O
Molecular Weight：448.6
Storage：Powder:-20℃，2 years
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1619903-54-6 |
| Name | LY-2857785 |
| Molecular Formula | C26H36N6O |
| Molecular Weight | 448.6 |
| Solubility | Soluble in DMSO ≥0.5mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years |
| MDL | MFCD28167812 |
| SMILES | CC(C1=C2C=C(C3=NC(N[C@H]4CC[C@H](NC5CCOCC5)CC4)=NC=C3)C=CC2=NN1C)C |
| Target Point | CDK7,8,9 |
| Passage | Cell Cycle |
| Background | LY2857785 is a type I reversible, ATP-competitive CDK9 inhibitor. |
| Biological Activity | LY2857785 is a type I reversible and competitive ATP kinase inhibitor against CDK9 (IC50 11 nM) and other transcription kinases CDK8 (IC50 16 nM)， and CDK7 (IC50 246 nM).[1] |
| Data Literature Source | [1]. Yin T， et al. A novel CDK9 inhibitor shows potent antitumor efficacy in preclinical hematologic tumor models. Mol Cancer Ther. 2014 Jun;13(6):1442-56. Mol Cancer Ther. 2014 Jun;13(6):1442-56. |
| Unit | Bottle |
| Specification | 2mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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