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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > DNA Damage & DNA Repai > Cyclophosphamide MonohydrateCAS：6055-19-2
Molecular Formula：C7H15Cl2N2O2P·H2O
Molecular Weight：279.1
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 6055-19-2 |
| Name | Cyclophosphamide Monohydrate |
| Molecular Formula | C7H15Cl2N2O2P·H2O |
| Molecular Weight | 279.1 |
| Solubility | Soluble in Water ≥5mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-015-4 |
| MDL | MFCD00149395 |
| SMILES | ClCCN(CCCl)P1(OCCCN1)=O.[H]O[H] |
| InChIKey | PWOQRKCAHTVFLB-UHFFFAOYSA-N |
| InChI | InChI=1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2 |
| PubChem CID | 22420 |
| Target Point | DNA Alkylator |
| Passage | DNA Damage/DNA Repair |
| Background | Cyclophosphamide Monohydrate is a DNA alkylating agent. Cross-linking with DNA, causing DNA strand breaks, causing mutations. Has antitumor and immunosuppressive activity. |
| Biological Activity | Cyclophosphamide hydrate 是一种合成的 DNA Alkylator，在化学上与氮芥类有关，具有抗肿瘤及免疫抑制活性。[1-3] |
| Data Literature Source | [1]. Schwartz PS，et al. Cyclophosphamide induces caspase 9-dependent apoptosis in 9L tumor cells. Mol Pharmacol. 2001 Dec;60(6):1268-1279. [2]. al-Jafari AA，et al. Inhibition of human acetylcholinesterase by cyclophosphamide. Toxicology. 1995 Jan 19;96(1):1-6. [3]. Harris RN，et al. Carbon tetrachloride-induced increase in the antitumor activity of cyclophosphamide in mice: a pharmacokineticstudy. Cancer Chemother Pharmacol. 1984;12(3):167-72. |
| Unit | Bottle |
| Specification | 100mg 200mg 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF
Click to check >>Author：Jiang XL; Tai H; Kuang JS; Zhang JY; Cui SC; Lu YX; Qi SB; Zhang SY; Li SM; Chen JP; Meng XS.
IF：0.0000
Publish_to：Aging (Albany NY)
PMID：36309912
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