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Procarbazine Hydrochloride

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Cat.No：IP2860 Solarbio

CAS：366-70-1

Molecular Formula：C₁₂H₁₉N₃O·HCl

Molecular Weight：257.76

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：≥98%

Appearance：White to off-white Solid

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Product Information

CAS	366-70-1
Name	Procarbazine Hydrochloride
Molecular Formula	C₁₂H₁₉N₃O·HCl
Molecular Weight	257.76
Solubility	Soluble in DMSO ≥10mg/mL
Purity	≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 206-678-6
MDL	MFCD00072082
SMILES	O=C(NC(C)C)C1=CC=C(CNNC)C=C1.Cl
InChIKey	DERJYEZSLHIUKF-UHFFFAOYSA-N
InChI	InChI=1S/C12H19N3O.ClH/c1-9(2)15-12(16)11-6-4-10(5-7-11)8-14-13-3;/h4-7,9,13-14H,8H2,1-3H3,(H,15,16);1H
PubChem CID	9703
Target Point	DNA Alkylator
Passage	DNA Damage/DNA Repair
Background	Procarbazine HCl is a multifunctional alkylating agent compound
Biological Activity	Procarbazine Hydrochloride 是一种烷化剂 (alkylator)，具有抗肿瘤的作用。[1-3]
Data Literature Source	[1]. Erikson JM，et al. Cytotoxicity and DNA damage caused by the azoxy metabolites of procarbazine in L1210 tumor cells. Cancer Res. 1989 Jan 1;49(1):127-33. [2]. Suzuki T，et al. Procarbazine genotoxicity in the MutaMouse; strong clastogenicity and organ-specific induction of lacZ mutations. Mutat Res. 1999 Aug 18;444(2):269-81. [3]. Weissenberg R，et al. Procarbazine effects on spermatogenesis in golden hamster: a flow cytometric evaluation. Arch Androl. 2002 Mar-Apr;48(2):91-100.
Unit	Bottle
Specification	50mg 10mM*1mL in DMSO 100mg 500mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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