Your Position: Home > Small Molecule Compounds > Inhibitors & Antagonists & Agonists > DNA Damage & DNA Repai > Chloroambucil

Chloroambucil

Manual Download

Cat.No：IC3240 Solarbio

CAS：305-03-3

Molecular Formula：C₁₄H₁₉Cl₂NO₂

Molecular Weight：304.21

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：≥98%

Appearance：White to yellow Solid

Qty：

Size：

Add to cart

Product Information Experimental Images Related Products Related Paper Technical Q&A

Product Information

CAS	305-03-3
Name	Chloroambucil
Molecular Formula	C₁₄H₁₉Cl₂NO₂
Molecular Weight	304.21
Solubility	Soluble in DMSO
Purity	≥98%
Appearance	White to yellow Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 206-162-0
MDL	MFCD00021783
SMILES	C1=CC(=CC=C1CCCC(=O)O)N(CCCl)CCCl
InChIKey	JCKYGMPEJWAADB-UHFFFAOYSA-N
InChI	InChI=1S/C14H19Cl2NO2/c15-8-10-17(11-9-16)13-6-4-12(5-7-13)2-1-3-14(18)19/h4-7H,1-3,8-11H2,(H,18,19)
PubChem CID	2708
Target Point	DNA Alkylator
Passage	DNA Damage/DNA Repair
Background	Chlorambucil is an alkylator with antitumor activity.
Biological Activity	Chlorambucil 是一种烷化剂 (alkylator)，具有抗肿瘤活性。Chloroambucil可通过碱化诱导的交叉相互作用剥夺DNA分子互补链的功能，然后抑制肿瘤细胞增殖。[1-2]
Data Literature Source	[1]. Guo JX，et al. Synergistic effects of chlorambucil and TRAIL on apoptosis and proliferation of Raji cells. Eur Rev Med Pharmacol Sci. 2017 Oct;21(20):4703-4710. [2]. Salem FS，et al. Biochemical and pathological studies on the effects of levamisole and chlorambucil on Ehrlich ascites carcinoma-bearing mice. Vet Ital. 2011 Jan-Mar;47(1):89-95.
Unit	Bottle
Specification	25mg 50mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.