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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > ME-0328CAS：1445251-22-8
Molecular Formula：C19H19N3O2
Molecular Weight：321.37
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1445251-22-8 |
| Name | ME-0328 |
| Molecular Formula | C19H19N3O2 |
| Molecular Weight | 321.37 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 808-923-8 |
| MDL | MFCD27991291 |
| SMILES | O=C(N[C@H](C1=CC=CC=C1)C)CCC(NC2=C3C=CC=C2)=NC3=O |
| Target Point | PARP |
| Passage | Cell Cycle;DNA Damage/DNA Repair; Epigenetics |
| Background | ME0328 is a potent and selective PARP inhibitor. |
| Biological Activity | ME0328 是一种有效的选择性 ARTD3/PARP3 抑制剂，IC50 为 0.89±0.28 μM[1]。 |
| IC50 | ARTD1/PARP1:6.3μM;ARTD2/PARP2:10.8μM;ARTD3/PARP3:0.89μM [1] |
| Data Literature Source | [1]. Lindgren AE，et al. PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3. ACS Chem Biol. 2013 Aug 16;8(8):1698-703 |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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