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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > DNA Damage & DNA Repai > CC-115CAS：1228013-15-7
Molecular Formula：C16H16N8O
Molecular Weight：336.35
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
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| CAS | 1228013-15-7 |
| Name | CC-115 |
| Molecular Formula | C16H16N8O |
| Molecular Weight | 336.35 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD29036965 |
| SMILES | O=C1CN=C2C(N1CC)=NC(C3=C(C)N=C(C4=NN=CN4)C=C3)=CN2 |
| Target Point | DNA-PK，mTOR，PI3Kα |
| Passage | DNA Damage/DNA Repair |
| Background | Compound 401 is a DNA-PK and mTOR inhibitor |
| Biological Activity | CC-115是DNA依赖性的蛋白激酶DNA-PK和哺乳动物雷帕霉素靶标mTOR的双重抑制剂，IC50分别为0.013 μM 和 0.021 μM。具有潜在的抗肿瘤活性。[1-2] |
| Data Literature Source | [1] Thijssen R，et al. Blood. 2016，128(4):574-83. [2] Mortensen DS，et al. J Med Chem. 2015，58(14):5599-608. |
| Unit | Bottle |
| Specification | 2mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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