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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Endocrinology & Hormones > AfiMoxifeneCAS：68392-35-8
Molecular Formula：C26H29NO2
Molecular Weight：387.51
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 68392-35-8 |
| Name | AfiMoxifene |
| Molecular Formula | C26H29NO2 |
| Molecular Weight | 387.51 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00278780 |
| SMILES | OC1=CC=C(/C(C2=CC=C(OCCN(C)C)C=C2)=C(C3=CC=CC=C3)\CC)C=C1 |
| Target Point | Estrogen Receptor/ERR |
| Passage | Endocrinology & Hormones |
| Background | It is an estrogen receptor modulator. |
| Biological Activity | 4-Hydroxytamoxifen (Afimoxifene) 是tamoxifen的活性代谢产物，是一种选择性的雌激素受体调节分子，相比于tamoxifen，它对雌激素受体有更高的亲和力，在乳腺癌的治疗和化学疗法中应用广泛。[1-3] |
| Data Literature Source | [1] Asp ML，et al. PLoS One. 2013，8(10):e78768. [2] Beland FA，et al. Carcinogenesis. 1999，20(3):471-477. [3] Davis KM，et al. Nat Chem Biol. 2015，11(5):316-8. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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