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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Endocrinology & Hormones > Cyproterone AcetateCAS：427-51-0
Molecular Formula：C24H29ClO4
Molecular Weight：416.94
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 427-51-0 |
| Name | Cyproterone Acetate |
| Molecular Formula | C24H29ClO4 |
| Molecular Weight | 416.94 |
| Solubility | Soluble in DMSO≥10mg/mL；Soluble in Ethanol≥1mg/mL；Soluble in Water＜1mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 207-048-3 |
| MDL | MFCD00192402 |
| SMILES | C[C@@]12C(C(Cl)=C[C@]3([H])[C@]2([H])C[C@@]4(C)[C@@]3([H])CC[C@]4(OC(C)=O)C(C)=O)=CC([C@H]5[C@@H]1C5)=O |
| InChIKey | UWFYSQMTEOIJJG-FDTZYFLXSA-N |
| InChI | InChI=1S/C24H29ClO4/c1-12(26)24(29-13(2)27)8-6-16-14-10-20(25)19-11-21(28)15-9-18(15)23(19,4)17(14)5-7-22(16,24)3/h10-11,14-18H,5-9H2,1-4H3/t14-,15+,16-,17-,18-,22-,23-,24-/m0/s1 |
| PubChem CID | 9880 |
| Target Point | Androgen Receptor |
| Passage | Endocrinology & Hormones |
| Background | Cyproterone Acetate is an androgen receptor antagonist. |
| Biological Activity | 是雄激素受体拮抗剂，IC50为7.1 nM，也是微弱的孕激素受体激动剂，具有微弱的孕激素和糖皮质激素活性。[1] |
| IC50 | Androgen Receptor: 7.1nM [1] |
| Data Literature Source | [1] Sonneveld E，et al. Toxicol Sci. 2005，83(1)，136-148. [2] Attardi BJ，et al. Mol Cell Endocrinol. 2010，328(1-2)，16-21. [3] Arafa NM. Pak J Biol Sci. 2010，13(20)，966-976. |
| Unit | Bottle |
| Specification | 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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