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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Endocrinology & Hormones > Aliskiren HemifumarateCAS：173334-58-2
Molecular Formula：C30H53N3O6·1/2C4H4O4
Molecular Weight：609.79
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 173334-58-2 |
| Name | Aliskiren Hemifumarate |
| Molecular Formula | C30H53N3O6·1/2C4H4O4 |
| Molecular Weight | 609.79 |
| Solubility | Soluble in Water/DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 630-415-8 |
| MDL | MFCD10566724 |
| SMILES | O=C(O)/C=C/C(O)=O.O=C(NCC(C)(C(N)=O)C)[C@@H](C[C@@H]([C@H](C[C@@H](C(C)C)CC1=CC=C(OC)C(OCCCOC)=C1)N)O)C(C)C.O=C(NCC(C)(C(N)=O)C)[C@H](C(C)C)C[C@H](O)[C@@H](N)C[C@@H](C(C)C)CC2=CC=C(OC)C(OCCCOC)=C2 |
| Target Point | Renin |
| Passage | Endocrinology & Hormones |
| Background | It is a direct inhibitor of renin. |
| Biological Activity | Aliskiren Hemifumarate是一种直接肾素抑制剂，IC50为1.5 nM。[1] |
| Data Literature Source | [1] Nakamura Y，et al. ACS Med Chem Lett，2012，3(9)，754–758. [2] Buczko W，et al. Pharmacol Rep，2008，60(5)，623-631. [3] Wood JM，et al. Biochem Biophys Res Commun，2003，308(4)，698-705. [4] Gradman AH，et al. Circulation，2005，111(8)，1012-1018. |
| Unit | Bottle |
| Specification | 25mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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