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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > GPCR & G Protein > Candesartan CilexetilCAS：145040-37-5
Molecular Formula：C33H34N6O6
Molecular Weight：610.66
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 145040-37-5 |
| Name | Candesartan Cilexetil |
| Molecular Formula | C33H34N6O6 |
| Molecular Weight | 610.66 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 627-030-2 |
| MDL | MFCD00871371 |
| SMILES | O=C(C1=C2C(N=C(OCC)N2CC3=CC=C(C4=CC=CC=C4C5=NNN=N5)C=C3)=CC=C1)OC(OC(OC6CCCCC6)=O)C |
| InChIKey | GHOSNRCGJFBJIB-UHFFFAOYSA-N |
| InChI | InChI=1S/C33H34N6O6/c1-3-42-32-34-28-15-9-14-27(31(40)43-21(2)44-33(41)45-24-10-5-4-6-11-24)29(28)39(32)20-22-16-18-23(19-17-22)25-12-7-8-13-26(25)30-35-37-38-36-30/h7-9,12-19,21,24H,3-6,10-11,20H2,1-2H3,(H,35,36,37,38) |
| PubChem CID | 2540 |
| Target Point | Angiotensin Receptor |
| Passage | GPCR & G Protein |
| Background | It is a specific, non-peptide angiopoietin II receptor (ATR) antagonist. |
| Biological Activity | Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist used mainly for the treatment of hypertension[1]. |
| Data Literature Source | [1]. Pfeffer，M.A.，et al.，Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme. Lancet，2003. 362(9386): p. 759-66. [2]. Wada，T.，et al.，Comparison of the antihypertensive effects of the new angiotensin II (AT1) receptor antagonist candesartan cilexetil (TCV-116) and the angiotensin converting enzyme inhibitor enalapril in rats. Hypertens Res，1996. 19(2): p. 75-81. |
| Unit | Bottle |
| Specification | 500mg 1g |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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