{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Endocrinology & Hormones > Endoxifen HydrochlorideCAS：1032008-74-4
Molecular Formula：C25H27NO2·HCl
Molecular Weight：409.95
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
Qty：
Size：
| CAS | 1032008-74-4 |
| Name | Endoxifen Hydrochloride |
| Molecular Formula | C25H27NO2·HCl |
| Molecular Weight | 409.95 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | OC1=CC=C(/C(C2=CC=C(OCCNC)C=C2)=C(C3=CC=CC=C3)\CC)C=C1.[H]Cl.[Z] |
| Target Point | Estrogen Receptor/ERR |
| Passage | Endocrinology & Hormones |
| Background | It is a potent and selective estrogen receptor antagonist. |
| Biological Activity | Endoxifen inhibited the hERG channel protein trafficking to the plasma membrane in a concentration-dependent manner. Endoxifen inhibited the hERG current by direct channel blockage and by the disruption of channel trafficking to the plasma membrane in a concentration-dependent manner. [1] |
| Data Literature Source | [1]. Chae YJ，et al. Endoxifen，the active metabolite of tamoxifen，inhibits cloned hERG potassium channels. Eur J Pharmacol. 2015 Apr 5;752:1-7. |
| Unit | Bottle |
| Specification | 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
