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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > DNA Damage & DNA Repai > AR-42CAS：935881-37-1
Molecular Formula：C18H20N2O3
Molecular Weight：312.36
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
Qty：
Size：
| CAS | 935881-37-1 |
| Name | AR-42 |
| Molecular Formula | C18H20N2O3 |
| Molecular Weight | 312.36 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 802-219-4 |
| MDL | MFCD17676151 |
| SMILES | CC([C@@H](C1=CC=CC=C1)C(NC2=CC=C(C=C2)C(NO)=O)=O)C |
| Target Point | HDAC |
| Passage | DNA Damage/DNA Repair;Epigenetics;NF-κB |
| Background | AR-42 is an HDAC inhibitor. |
| Biological Activity | AR-42 (HDAC-42) 是一种HDAC抑制剂，IC50为30 nM。[1] |
| Data Literature Source | [1] Lu Q，et al. J Med Chem，2005，48(17)，5530-5535. [2] Chen CS，et al. J Biol Chem，2005，280(46)，38879-38887. [3] Kulp SK，et al. Clin Cancer Res，2006，12(17)，5199-5206. [4] Chen CS，et al. Cancer Res，2007，67(11)，5318-5327. [5] Sargeant AM，et al. Cancer Res，2008，68(10)，3999-4009. [6] Lin TY，et al. Blood，2010，115(21)，4217-4225. [7] Lucas DM，et al. PLoS One，2010，5(6)，e10941. |
| Unit | Bottle |
| Specification | 2mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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