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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Epigenetics > CPI-637CAS：1884712-47-3
Molecular Formula：C22H22N6O
Molecular Weight：386.45
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1884712-47-3 |
| Name | CPI-637 |
| Molecular Formula | C22H22N6O |
| Molecular Weight | 386.45 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD30489741 |
| SMILES | O=C1NC2=CC=CC(C3=CC4=C(N(C)N=C4C5=CN(C)N=C5)C=C3)=C2N[C@H](C)C1 |
| Target Point | CBP，EP300，Epigenetic Reader Domain |
| Passage | Epigenetics |
| Background | CPI-637 is a selective, cell-active CBP/EP300 bromodomain protein inhibitor. |
| Biological Activity | CPI-637是一种选择性的、具有细胞活性的CBP/EP300溴结构域蛋白抑制剂。在TR-FRET检测中，CPI-637对CBP和EP300的IC50分别为0.03 μM和0.051 μM。在其他溴区结构域中，它具有高度选择性，相较而言，对BRD9的生化活性比较突出。[1] |
| Data Literature Source | [1] Taylor AM，et al. ACS Med Chem Lett. 2016，7(5):531-6. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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