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My CartCAS：128446-36-6
Molecular Formula：No data available
Molecular Weight：~1320
Storage：Store at RT，2 years
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 128446-36-6 |
| Name | Methyl-β-cyclodextrin |
| Molecular Formula | No data available |
| Molecular Weight | ~1320 |
| Solubility | Soluble in Water ≥100mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Store at RT，2 years |
| EC | EINECS 1308068-626-2 |
| MDL | MFCD00074980 |
| SMILES | CO[C@@H]1[C@H](O[R])[C@H](O[R])[C@@H](C)C(CO[R])O1.[7].[R=H or -CH3] |
| InChIKey | YZOUYRAONFXZSI-SBHWVFSVSA-N |
| InChI | InChI=1S/C54H94O35/c1-64-36-28(63)30-21(14-56)76-48(36)83-29-20(13-55)77-49(37(65-2)27(29)62)85-31-22(15-57)79-51(44(72-9)38(31)66-3)87-33-24(17-59)81-53(46(74-11)40(33)68-5)89-35-26(19-61)82-54(47(75-12)42(35)70-7)88-34-25(18-60)80-52(45(73-10)41(34)69-6)86-32-23(16-58)78-50(84-30)43(71-8)39(32)67-4/h20-63H，13-19H2，1-12H3/t20-，21-，22-，23-，24-，25-，26-，27-，28-，29-，30-，31-，32-，33-，34-，35-，36+，37+，38-，39-，40-，41-，42-，43+，44+，45+，46+，47+，48-，49-，50-，51-，52-，53-，54-/m1/s1 |
| PubChem CID | 51051622 |
| Background | It is a water-Soluble cycloheptose, which has a solubilizing effect on non-polar substances. Also a cholesterol remover, mainly used to destroy lipid raft. |
| Biological Activity | Methyl-β-cyclodextrin，是一种环状七糖，可有效的消除细胞中的胆固醇; 抑制PEL细胞生长的IC50值为3.33-4.23 mM。[1-2] |
| IC50 | 3.33-4.23mM(PEL cell growth)[1] |
| Data Literature Source | [1]. Gotoh K，et al. The antitumor effects of methyl-β-cyclodextrin against primary effusion lymphoma via the depletion of cholesterol from lipid rafts. Biochem Biophys Res Commun. 2014 Dec 12;455(3-4):285-9. [2]. Tiwari G，et al. Cyclodextrins in delivery systems: Applications. J Pharm Bioallied Sci. 2010 Apr;2(2):72-9 |
| Unit | Bottle |
| Specification | 1g 2g 5g |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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