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Methyldopa

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Cat.No：IM2680 Solarbio

CAS：555-30-6

Molecular Formula：C₁₀H₁₃NO₄

Molecular Weight：211.21

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：≥98%

Appearance：White to off-white Solid

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Product Information

CAS	555-30-6
Name	Methyldopa
Molecular Formula	C₁₀H₁₃NO₄
Molecular Weight	211.21
Solubility	Soluble in DMSO ≥10mg/mL
Purity	≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 209-089-2
MDL	MFCD00004186
SMILES	OC1=C(O)C=CC(C[C@@](C)(C(O)=O)N)=C1
InChIKey	CJCSPKMFHVPWAR-JTQLQIEISA-N
InChI	InChI=1S/C10H13NO4/c1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6/h2-4,12-13H,5,11H2,1H3,(H,14,15)/t10-/m0/s1
PubChem CID	38853
Target Point	Adrenergic Receptor，DOPA decarboxylase
Passage	Metabolic Enzyme&Protease;Endocrinology & Hormones;GPCR & G Protein;Neuronal Signaling
Background	Methyldopa is a selective agonist for α2-adrenergic receptors and a competitive inhibitor of DOPA decarboxylase.
Biological Activity	Methyldopa (L-(-)-α-Methyldopa) 是一种 α-肾上腺素能激动剂 (对 α2- adrenergic receptors 有选择性)。是DOPA 脱羧酶竞争性抑制剂，ED50为21.8 mg/kg。[1-2]
Data Literature Source	[1]. Sweet CS. New centrally acting antihypertensive drugs related to methyldopa and clonidine. Hypertension. 1984;6(5 Pt 2):II51-II56. [2]. DAY MD，RAND MJ. SOME OBSERVATIONS ON THE PHARMACOLOGY OF ALPHA-METHYLDOPA. Br J Pharmacol Chemother. 1964 Feb;22(1):72-86.
Unit	Bottle
Specification	200mg 500mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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