TTNPB
Cat.No:IT2160 Solarbio
CAS:71441-28-6
Molecular Formula:C24H28O2
Molecular Weight:348.48
Storage:Powder:-20℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:White to yellow Solid
Qty:
Size:
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Small Molecule Compounds >
Inhibitors & Antagonists & Agonists >
Metabolic Enzyme & Protease >
TTNPBCAS:71441-28-6
Molecular Formula:C24H28O2
Molecular Weight:348.48
Storage:Powder:-20℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:White to yellow Solid
Qty:
Size:
CAS | 71441-28-6 |
Name | TTNPB |
Molecular Formula | C24H28O2 |
Molecular Weight | 348.48 |
Solubility | Soluble in DMSO ≥1mg/mL(Need ultrasonic) |
Purity | ≥98% |
Appearance | White to yellow Solid |
Storage | Powder:-20℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
MDL | MFCD00673917 |
SMILES | CC(=CC1=CC=C(C=C1)C(=O)O)C2=CC3=C(C=C2)C(CCC3(C)C)(C)C |
Target Point | RAR |
Passage | Metabolic Enzyme&Protease |
Background | TTNPB is a potent RAR agonist. |
Biological Activity | TTNPB 是一种有效的 RAR 激动剂。使用人RARs进行竞争性结合实验中,作用于RARα,RARβ和RARγ,IC50 分别为 5.1 nM,4.5 nM 和 9.3 nM。[1] |
IC50 | 5.1nM(RARα),4.5nM(RARβ),9.3nM(RARγ)[1] |
Data Literature Source | [1]. Pignatello MA,et al. Multiple factors contribute to the toxicity of the aromatic retinoid,TTNPB (Ro 13-7410): binding affinities and disposition. Toxicol Appl Pharmacol. 1997 Feb;142(2):319-27 |
Unit | Bottle |
Specification | 5mg 10mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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