| Gene Name |
ACTL6A |
| Synonyms |
actin like 6A，Actin like protein 6A，Actin related protein Baf53a，ACTL6，ACTL6A，Arp4，ARPN BETA，ArpNbeta，BAF53，BAF53A，BRG1 associated factor 53A，INO80 complex subunit K，INO80K |
| English Name |
Recombinant human ACTL6A protein |
| Full Name |
actin-like 6A |
| Chinese Name |
肌动蛋白样6A |
| Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
| Purity |
≥85% by SDS-PAGE. |
| Storage |
Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
| Concentration |
1mg/ml by SDS-PAGE. |
| Swiss Prot |
O96019 |
| Gene ID |
86 |
| Reactivity |
Human Mouse (Monkey) |
| Molecular Weight |
33kDa |
| Interval Range |
1-300aa |
| Background |
This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins.Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature.The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling.This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S.cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression.Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix.Three transcript variants that encode two different protein isoforms have been described. |
| Application |
Immunology research |
| Source |
E.coli |
| Purification Method |
NI-NTA affinity purification |
| Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| Endotoxin |
Not measured |
| Biological Activity |
N0 |
| Lable Information |
With a 6×His tag at the N/C-terminus. |
| Unit |
Piece |
| Specification |
10ug 50ug 100ug 1mg |
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