Gene Name |
TEAD2 |
Synonyms |
TEAD2;ETF;TEAD-2;TEF-4;TEF4;TEA domain transcription factor 2 |
English Name |
Recombinant human TEAD2 protein |
Full Name |
TEA domain family member 2 |
Chinese Name |
TEA结构域家族成员2 |
Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Purity |
≥85% by SDS-PAGE. |
Storage |
Reconstituted protein solution can be stored at 4-7℃ for 2-7 days, stored at < -20℃ for 1 year. |
Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
Concentration |
1mg/ml by SDS-PAGE. |
Swiss Prot |
Q15562 |
Gene ID |
8463 |
Reactivity |
Human Mouse |
Molecular Weight |
35kDa |
Interval Range |
131-447aa |
Background |
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction.Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3').May be involved in the gene regulation of neural development.Binds to the M-CAT motif. |
Application |
Immunology research |
Source |
E.coli |
Purification Method |
NI-NTA affinity purification |
Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.) |
Endotoxin |
Not measured |
Biological Activity |
No activity experimental data, to be verified. |
Lable Information |
With a 6×His tag at the N/C-terminus. |
Unit |
Piece |
Specification |
10ug 50ug 100ug 1mg |