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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > MAPK > BI-78D3CAS：883065-90-5
Molecular Formula：C13H9N5O5S2
Molecular Weight：379.37
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 883065-90-5 |
| Name | BI-78D3 |
| Molecular Formula | C13H9N5O5S2 |
| Molecular Weight | 379.37 |
| Solubility | Soluble in DMSO ≥5mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD01313575 |
| SMILES | O=C1N(C2=CC=C(OCCO3)C3=C2)C(SC4=NC=C([N+]([O-])=O)S4)=NN1 |
| Target Point | JNK |
| Passage | MAPK |
| Background | BI-78D3 is a novel, potent and competitive JNK inhibitor |
| Biological Activity | BI-78D3是一种竞争性的JNK抑制剂，IC50为280 nM，其选择性比对p38α高100倍，对mTOR和PI-3K没有活性。[1] |
| IC50 | JNK: 280nM [1] |
| Data Literature Source | [1] Stebbins JL，et al. Proc Natl Acad Sci U S A. 2008，105(43):16809-16813. |
| Unit | Bottle |
| Specification | 10mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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