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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > PiperlongumineCAS：20069-09-4
Molecular Formula：C17H19NO5
Molecular Weight：317.34
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to yellow Solid
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| CAS | 20069-09-4 |
| Name | Piperlongumine |
| Molecular Formula | C17H19NO5 |
| Molecular Weight | 317.34 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00075706 |
| SMILES | O=C1C=CCCN1C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O |
| Target Point | Others |
| Passage | Immunology & Inflammation |
| Background | It has various biological activities such as anti-inflammatory, antibacterial, anti-angiogenesis, antioxidant, anti-tumor and anti-diabetic. |
| Biological Activity | Piperlongumine 是从荜茇中得到的生物碱[1]，具有抗炎、抗菌、抗血管生成、抗氧化、抗肿瘤和抗糖尿病等活性[2]。在肿瘤细胞中，Piperlongumine 能够诱导 ROS 和凋亡[1]。Piperlongumine 具有抗心肌纤维化的作用，通过抑制 ERK1/2 信号通路抑制肌成纤维细胞的转化[2]。 |
| Data Literature Source | [1]. Karki K，et al. Piperlongumine Induces Reactive Oxygen Species (ROS)-Dependent Downregulation of Specificity Protein Transcription Factors. [2]. Wu X，e，t al. Piperlongumine inhibits angiotensin II-induced extracellular matrix expression in cardiac fibroblasts. J Cell Biochem. 2018 Dec;119(12):10358-10364 |
| Unit | Bottle |
| Specification | 5mg 10mg 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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