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My Cart> Cell Biology > Cell Detection > Cell Growth Factor > Recombinant Human Pyruvate kinase PKM/PKM2Purity：≥95% as determined by reducing SDS-PAGE.
Storage：Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Appearance：Supplied as a 0.2 μm filtered solution of 20mM Tris- HCl, 50mM NaCl, 0.05% Brij-35, 1mM DTT, pH7.5.
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| Appearance | Supplied as a 0.2 μm filtered solution of 20mM Tris- HCl, 50mM NaCl, 0.05% Brij-35, 1mM DTT, pH7.5. |
| Purity | ≥95% as determined by reducing SDS-PAGE. |
| Storage | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| Background | Pyruvate kinase isoform M2 (PKM2) is a member of the pyruvate kinase (PK) family，a pivotal glycolytic enzyme that is consistently changed during tumorigenesis.PKM2 is expressed in some differentiated tissues，such as lung，fat tissue，retina，and pancreatic islets.As the rate-controlling enzyme in glycolysis，PKM2，has also been found to be expressed in embryonic，proliferating，and tumor cells，and it has been considered to be crucial for the metabolism and growth of tumor cells.Recent studies have shown that PKM2 promotes cell proliferation and suppresses cell apoptosis in various tumors.In addition，it has been reported that the PKM2 knockdown affects the Akt and ERK protein kinases. |
| Source | E.coli |
| Endotoxin | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| Unit | Piece |
| Specification | 10ug 50ug 500ug 1mg |
Cell growth factor
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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