{{cart_num}}
My Cart> Cell Biology > Cell Detection > Cell Growth Factor > Recombinant Mouse CD155/PVR/Poliovirus Receptor/Nectin-Like Protein 5/NECL-5/PVS
Purity：≥95% as determined by reducing SDS-PAGE.
Storage：Powder:＜-20℃ for long store;RT，3 weeks.Liquid:4-7℃，2-7 days;＜-20℃，3 months.
Appearance：Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Qty：
Size：
| Appearance | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| Purity | ≥95% as determined by reducing SDS-PAGE. |
| Storage | Powder:＜-20℃ for long store;RT，3 weeks.Liquid:4-7℃，2-7 days;＜-20℃，3 months. |
| Background | Mouse poliovirus receptor (PVR，CD155) is a type I transmembrane (TM) glycoprotein that is a member of the nectin-related family of adhesion proteins within the immunoglobulin superfamily.It binds other molecules including vitronectin，Nectin3，DNAM1，CD96，and TIGIT，but does not bind homotypically.CD155 includes a 28 aa signal sequence，a 318 aa extracellular domain (ECD) with one N-terminal V-type and two C2-type Ig-like domains，a 24 aa TM segment and a 38 aa cytoplasmic tail.Epithelial，endothelial，and many immune cells show low CD155 expression.It is up-regulated on endothelia by IFNγ，and is highly expressed on immature thymocytes，lymph node dendritic cells，and tumor cells of epithelial and neuronal origin.On migrating cells，it is concentrated at the leading edge，where it binds basement membrane vitronectin，recruits Nectin-3-expressing cells，and cooperates with PDGF and integrin αvβ3 to promote cell migration.Binding of monocyte DNAM-1 to endothelial cell CD155 promotes transendothelial migration.Enhanced CD155 expression in tumor cells contributes to loss of contact inhibition and increased migration，but also allows tumor cell recognition and killing by DNAM-1or CD96 expressing NK cells. |
| Source | Human Cells |
| Solvent | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Endotoxin | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| Unit | Piece |
| Specification | 10ug 50ug 500ug 1mg |
Cell growth factor
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no experimental images.
Sorry, there is no more information.
Sorry, there is no more information.
