ATI-2341
Cat.No:IA4180 Solarbio
CAS:1337878-62-2
Molecular Formula:C104H178N26O25S2
Molecular Weight:2256.82
Storage:Powder:-20℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥96%
Appearance:Solid
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ATI-2341CAS:1337878-62-2
Molecular Formula:C104H178N26O25S2
Molecular Weight:2256.82
Storage:Powder:-20℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥96%
Appearance:Solid
Qty:
Size:
CAS | 1337878-62-2 |
Name | ATI-2341 |
Molecular Formula | C104H178N26O25S2 |
Molecular Weight | 2256.82 |
Solubility | Soluble in DMSO ≥10mg/mL |
Purity | ≥96% |
Appearance | Solid |
Storage | Powder:-20℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
MDL | MFCD30182359 |
SMILES | CCCCCCCCCCCCCCCC(=O)NC(CCSC)C(=O)NCC(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CO)C(=O)NC(CCSC)C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(C)C)C(=O)O |
Target Point | CXCR |
Passage | Immunology & Inflammation;GPCR & G Protein |
Background | ATI-2341 is a potent and functionally selective allosteric agonist of the C-X-C chemokine receptor type 4 (CXCR4). ATI-2341 activates inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization. |
Biological Activity | ATI-2341,一种靶向C-X-C 4型趋化因子受体(CXCR4)的肽段,是一个变构受体激动剂,能够激活异源三聚体G蛋白(Gi)、抑制cAMP生成以及诱导钙动员。[1] |
Data Literature Source | [1] Tchernychev B,et al. Proc Natl Acad Sci U S A. 2010,107(51) |
Unit | Bottle |
Specification | 1mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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