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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > Ketorolac Tromethamine SaltCAS：74103-07-4
Molecular Formula：C19H24N2O6
Molecular Weight：376.4
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 74103-07-4 |
| Name | Ketorolac Tromethamine Salt |
| Molecular Formula | C19H24N2O6 |
| Molecular Weight | 376.4 |
| Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00887595 |
| SMILES | O=C(C1C2=CC=C(C(C3=CC=CC=C3)=O)N2CC1)O.OCC(CO)(N)CO |
| Target Point | COX |
| Passage | Immunology & Inflammation |
| Background | It is a non-steroidal anti-inflammatory agent and a non-selective COX inhibitor. |
| Biological Activity | Ketorolac tromethamine salt 是一种非甾体抗炎剂，为非选择性的 COX 抑制剂，对 COX-1 和 COX-2 的 IC50 值分别为 20 nM 和 120 nM。[1-3] |
| Data Literature Source | [1]. Waterbury LD，et al. Comparison of cyclooxygenase inhibitory activity and ocular anti-inflammatory effects of ketorolac tromethamine and bromfenac sodium. Curr Med Res Opin. 2006 Jun;22(6):1133-40. [2]. Fracon RN，et al. Treatment with paracetamol，ketorolac or etoricoxib did not hinder alveolar bone healing: a histometric study in rats. J Appl Oral Sci. 2010 Dec;18(6):630-4. [3]. Hsieh YC，et al. Intrathecal ketorolac pretreatment reduced spinal cord ischemic injury in rats. Anesth Analg. 2005 Apr;100(4):1134-9 |
| Unit | Bottle |
| Specification | 100mg 500mg 1g |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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