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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > WZ-811CAS：55778-02-4
Molecular Formula：C18H18N4
Molecular Weight：290.36
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 55778-02-4 |
| Name | WZ-811 |
| Molecular Formula | C18H18N4 |
| Molecular Weight | 290.36 |
| Solubility | Soluble in DMSO ≥1mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-256-5 |
| MDL | MFCD00040744 |
| SMILES | C1(CNC2=NC=CC=C2)=CC=C(CNC3=NC=CC=C3)C=C1 |
| Target Point | CXCR4 |
| Passage | Immunology & Inflammation;GPCR & G Protein |
| Background | WZ-811 is a potent CXCR4 antagonist. |
| Biological Activity | WZ811 是一种有效的 CXCR4 拮抗剂，能够抑制 TN14003 与 CXCR4 结合，EC50 值为 0.3 nM。[1-2] |
| Data Literature Source | [1]. WZ811，et al. Discovery of small molecule CXCR4 antagonists. J Med Chem. 2007 Nov 15;50(23):5655-64. [2]. Li SH，et al. Suppression of chronic lymphocytic leukemia progression by CXCR4 inhibitor WZ811. Am J Transl Res. 2016 Sep 15;8(9):3812-3821 |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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