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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Epigenetics > MI463CAS：1628317-18-9
Molecular Formula：C24H23F3N6S
Molecular Weight：484.54
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1628317-18-9 |
| Name | MI463 |
| Molecular Formula | C24H23F3N6S |
| Molecular Weight | 484.54 |
| Solubility | Soluble in DMSO ≥10mg/mL;Soluble in Water ＜ 1mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD28506301 |
| SMILES | FC(F)(F)CC(S1)=CC2=C1N=CN=C2NC3CCN(CC4=CC=C(NC(C#N)=C5)C5=C4C)CC3 |
| Target Point | Menin-MLL interaction |
| Passage | Epigenetics |
| Background | MI-463 is a potent inhibitor of Menin-mLL interaction. |
| Biological Activity | MI-463 is a highly potent and orally bioavailable small molecule inhibitor of the menin-mLL interaction.[1] |
| Data Literature Source | [1]. Borkin D， et al. Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo. Cancer Cell. 2015 Apr 13;27(4):589-602. |
| Unit | Bottle |
| Specification | 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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