| Gene Name |
CYP1A1 |
| Synonyms |
AHH;AHRR;Aryl hydrocarbon hydroxylase;CP11;CP1A1_HUMAN;CYP 1;CYP1;cyp1a1;CYPIA1;Cytochrome P1 450 dioxin inducible;Cytochrome P1-450;Cytochrome P450 1A1;Cytochrome P450 family 1 subfamily A polypeptide 1;Cytochrome P450 form 6;Cytochrome P450 subfamily I (aromatic compound inducible) polypeptide 1;Cytochrome P450-C;Cytochrome P450-P1;Flavoprotein-linked monooxygenase;Microsomal monooxygenase;P1 450;P450 C;P450 form 6;P450 P1;P450DX;Xenobiotic monooxygenase; |
| English Name |
Recombinant human CYP1A1 protein |
| Full Name |
cytochrome P450，family 1，subfamily A，polypeptide 1 |
| Chinese Name |
细胞色素P450家族1亚家族A多肽1 |
| Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
| Purity |
≥85% by SDS-PAGE. |
| Storage |
Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
| Concentration |
1mg/ml by SDS-PAGE. |
| Swiss Prot |
P04798 |
| Gene ID |
1543 |
| Reactivity |
Human Mouse Rat (Pig Dog Rabbit Monkey Monkey) |
| Molecular Weight |
40kDa |
| Interval Range |
61-410aa |
| Background |
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Application |
Immunology research |
| Source |
E.coli |
| Purification Method |
NI-NTA affinity purification |
| Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| Endotoxin |
Not measured |
| Biological Activity |
N0 |
| Lable Information |
With a 6×His tag at the N/C-terminus. |
| Unit |
Piece |
| Specification |
10ug 50ug 100ug 1mg |
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