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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Membrane Transporter & Ion Channel > MethocarbamolCAS：532-03-6
Molecular Formula：C11H15NO5
Molecular Weight：241.24
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 532-03-6 |
| Name | Methocarbamol |
| Molecular Formula | C11H15NO5 |
| Molecular Weight | 241.24 |
| Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 208-524-3 |
| MDL | MFCD00057662 |
| SMILES | OC(COC1=CC=CC=C1OC)COC(N)=O |
| InChIKey | GNXFOGHNGIVQEH-UHFFFAOYSA-N |
| InChI | InChI=1S/C11H15NO5/c1-15-9-4-2-3-5-10(9)16-6-8(13)7-17-11(12)14/h2-5,8,13H,6-7H2,1H3,(H2,12,14) |
| PubChem CID | 4107 |
| Target Point | Carbonic Anhydrase，Sodium Channel(Nav1.4) |
| Passage | Membrane Transporter&Ion Channel |
| Background | Methocarbamol is a carbonic anhydrase inhibitor that also reversibly affects voltage-dependent Nav1.4 channel inactivation. Potential for use in muscle spasticity and pain syndrome research. |
| Biological Activity | Methocarbamol is an orally active central muscle relaxant and blocks muscular Nav1.4 channel. Methocarbamol reversibly affects voltage dependence of inactivation of Nav1.4 channel. Methocarbamol has the potential for muscle spasms and pain syndromes research[1-3]. |
| Data Literature Source | [1]. Bruce，R.B.，L.B. Turnbull，and J.H. Newman，Metabolism of methocarbamol in the rat，dog，and human. J Pharm Sci，1971. 60(1): p. 104-6. [2]. Sica，D.A.，et al.，Pharmacokinetics and protein binding of methocarbamol in renal insufficiency and normals. Eur J Clin Pharmacol，1990. 39(2): p. 193-4. [3]. Yaxin Zhang，et al. Methocarbamol blocks muscular Na v 1.4 channels and decreases isometric force of mouse muscles. Muscle Nerve. 2020 Oct 11. |
| Unit | Bottle |
| Specification | 50mg 100mg 250mg 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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