Tranylcypromine Hemisulfate
Cat.No:IT2240 Solarbio
CAS:13492-01-8
Molecular Formula:C18H24N2O4S
Molecular Weight:364.46
Storage:Powder:2-8℃,2 years
Purity:≥98%
Appearance:White to off-white Solid
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Tranylcypromine HemisulfateCAS:13492-01-8
Molecular Formula:C18H24N2O4S
Molecular Weight:364.46
Storage:Powder:2-8℃,2 years
Purity:≥98%
Appearance:White to off-white Solid
Qty:
Size:
CAS | 13492-01-8 |
Name | Tranylcypromine Hemisulfate |
Molecular Formula | C18H24N2O4S |
Molecular Weight | 364.46 |
Solubility | Soluble in DMSO ≥0.1mg/mL(Need ultrasonic) |
Purity | ≥98% |
Appearance | White to off-white Solid |
Storage | Powder:2-8℃,2 years |
EC | EINECS 236-807-1 |
MDL | MFCD00079222 |
SMILES | N[C@H]1[C@H](C2=CC=CC=C2)C1.[0.5H2SO4] |
Target Point | Monoamine Oxidase(MAO) |
Passage | Neuronal Signaling |
Background | Tranylcypromine Hemisulfate is an irreversible, nonselective MAO inhibitor. |
Biological Activity | Tranylcypromine hemisulfate是一种用于治疗抑郁症的不可逆,非选择性 MAO 抑制剂。[1-4] |
Data Literature Source | [1]. Caraci F,et al. Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity. Eur J Pharmacol. 2015 Oct 5;764:256-263. [2]. Sun Q,et al. Tranylcypromine,a lysine-specific demethylase 1 (LSD1) inhibitor,suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis. Reprod Biol Endocrinol. 2016 Apr 9;14:17. [3]. Tsutsumi T,et al. Potential Neuroprotective Effects of an LSD1 Inhibitor in Retinal Ganglion Cells via p38 MAPK Activity. Invest Ophthalmol Vis Sci. 2016 Nov 1;57(14):6461-6473. [4]. Romanczyk TB,et al. The antidepressant tranylcypromine alters cellular proliferation and migration in the adult goldfish brain. Anat Rec (Hoboken). 2014 Oct;297(10):1919-26 |
Unit | Bottle |
Specification | 100mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
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