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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > 8-OH-DPATCAS：78950-78-4
Molecular Formula：C16H25NO
Molecular Weight：247.38
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥95%
Appearance：White to off-white Solid
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| CAS | 78950-78-4 |
| Name | 8-OH-DPAT |
| Molecular Formula | C16H25NO |
| Molecular Weight | 247.38 |
| Solubility | Soluble in DMSO |
| Purity | ≥95% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | CCCN(CCC)C1CCC2=C(C1)C(=CC=C2)O |
| InChIKey | ASXGJMSKWNBENU-UHFFFAOYSA-N |
| InChI | InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 |
| PubChem CID | 1220 |
| Target Point | 5-HT Receptor |
| Passage | Neuronal Signaling;GPCR & G Protein |
| Background | 8-OH-DPAT is a potent and selective 5-HT agonist. |
| Biological Activity | 8-OH-DPAT (8-Hydroxy-DPAT)是一种经典的5-HT1A激动剂，pIC50为8.19。对5-HT1结合位点亚型具有近1000倍选择性，其半衰期为1.5小时。[1-4] |
| Data Literature Source | [1] Middlemiss DN，et al. Eur J Pharmacol. 1983，90(1):151-3. [2] Montgomery AM，et al. J Neural Transm Gen Sect. 1991，83(1-2):139-48. [3] Scrogin KE. Am J Physiol Regul Integr Comp Physiol. 2003，284(3):R782-91. [4] Thampi P，et al. PLoS One. 2012，7(4):e34468. |
| Unit | Bottle |
| Specification | 5mg 10mM*1mL in DMSO 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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