Gene Name |
SKAP2 |
Synonyms |
SKAP2;PRAP;RA70;SAPS;SCAP2;SKAP-HOM;SKAP55R;src kinase-associated phosphoprotein 2 |
English Name |
Recombinant human SKAP2 protein |
Full Name |
src kinase associated phosphoprotein 2 |
Chinese Name |
SRC激酶相关磷酸蛋白2 |
Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Purity |
≥85% by SDS-PAGE. |
Storage |
Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year. |
Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
Concentration |
1mg/ml by SDS-PAGE. |
Swiss Prot |
O75563 |
Gene ID |
8935 |
Reactivity |
Human Mouse Rat (Bovine Gorilla Zebrafish) |
Molecular Weight |
41kDa |
Interval Range |
1-359aa |
Background |
The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases.It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system.This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus.Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly.Alternative splicing results in multiple transcript variants encoding different isoforms. |
Application |
Immunology research |
Source |
E.coli |
Purification Method |
NI-NTA affinity purification |
Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
Endotoxin |
Not measured |
Biological Activity |
N0 |
Lable Information |
With a 6×His tag at the N/C-terminus. |
Unit |
Piece |
Specification |
10ug 50ug 100ug 1mg |