Gene Name |
TTR |
Synonyms |
CTS,CTS1,HsT2651,PALB |
English Name |
Recombinant human TTR protein |
Full Name |
transthyretin |
Chinese Name |
甲状腺素转运蛋白 |
Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Purity |
≥85% by SDS-PAGE. |
Storage |
Reconstituted protein solution can be stored at 4-7℃ for 2-7 days, stored at < -20℃ for 1 year. |
Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
Concentration |
1mg/ml by SDS-PAGE. |
Swiss Prot |
P02766 |
Gene ID |
7276 |
Reactivity |
Human Mouse (Bovine A.thaliana) |
Molecular Weight |
16kDa |
Interval Range |
1-147aa |
Background |
This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid.The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid.It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein.The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis.Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic.The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome. |
Application |
Immunology research |
Source |
E.coli |
Purification Method |
NI-NTA affinity purification |
Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 10μg/ml. Dissolve the lyophilized protein in distilled water.) |
Endotoxin |
Not measured |
Biological Activity |
No activity experimental data, to be verified. |
Lable Information |
With a 6×His tag at the N/C-terminus. |
Unit |
Piece |
Specification |
10ug 50ug 100ug 1mg |