CAS号 | 产品货号 | 产品名称 | 分子式 | 分子量 | 对应靶点 | 产品描述 |
22427-39-0 | IG0240 | Ginsenoside Rg1;人参皂苷Rg1 | C42H72O14 | 801.01 | Amyloid-β | 通过降低大脑Aβ水平来发挥作用。 |
52286-59-6 | IG0650 | Ginsenoside Re;人参皂苷Re | C48H82O18 | 947.15 | Amyloid-β | Ginsenoside Re可降低β-淀粉样蛋白(Aβ),抑制 JNK和NF-κB。 |
80418-24-2 | IN0240 | Notoginsenoside R1;三七皂苷R1 | C47H80O18 | 933.13 | Amyloid-β;TNF-α | 是三七中的主要生物活性成分,据报道具有一定的神经元保护作用。通过上抑制Aβ积累对阿尔茨海默病 APP/PS1小鼠模型具有保护作用。 |
20736-08-7 | IS0520 | Saikosaponin C;柴胡皂苷C | C48H78O17 | 927.12 | Amyloid-β;tau protein | 是柴胡中的活性成分,在阿尔滋海默症中主要靶作用于amyloid beta和tau蛋白。 |
134308-13-7 | IT2230 | Tolcapone;托卡朋 | C14H11NO5 | 273.24 | Aβ42 | 是一种Aβ42寡聚和原纤维形成的有效抑制剂 |
97657-92-6 | IL0790 | Latrepirdine 2HCl | C21H25N3·2HCl | 392.37 | Amyloid-β | 刺激淀粉样前体蛋白 (APP) 分解代谢和β-淀粉样蛋白(amyloid-β,Aβ)分泌。 |
425386-60-3 | IS1540 | Semagacestat;司马西特 | C19H27N3O4 | 361.44 | Amyloid β;γ-secretase | 是一种 γ-secretase 抑制剂,抑制β-amyloid (Aβ42),Aβ38和Aβ40。可用于阿尔茨海默病的相关研究。 |
58749-23-8 | IL2000 | Licochalcone B;甘草查尔酮 B | C16H14O5 | 286.28 | Amyloid β | 抑制淀粉样蛋白β(amyloid β;Aβ420)自聚集作用并分解预先形成的Aβ42原纤维,通过螯合金属离子减少金属诱导的Aβ42聚集。 |
本套装精选了数种靶向Amyloid-β的化合物,可用于阿兹海默症的相关研究,便于客户进行初筛等操作。客户也可根据自己的需求灵活定制专属Kit。 |
Remark:
These protocols are for reference only. Solarbio does not independently validate these
methods.
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