CAS号 | 产品货号 | 产品名称 | 分子式 | 分子量 | 对应靶点 | 产品描述 |
23180-57-6 | IP0030 | Paeoniflorin;芍药苷 | C23H28O11 | 480.46 | HIF/HIF Prolyl-Hydroxylase | 据报道,芍药苷可通过mTOR依赖的通路抑制 HIF-1α。 |
89464-63-1 | ID0540 | DMOG;二甲基乙二酰氨基乙酸 | C6H9NO5 | 175.14 | HIF/HIF Prolyl-Hydroxylase | 是竞争型的 HIF-1α脯氨酰羟化酶 (HIF-PH) 抑制剂。 |
5302-45-4 | IO0320 | β-n-Oxalylamino-l-alanine;三七素 | C5H8N2O5 | 176.13 | HIF/HIF Prolyl-Hydroxylase | 是一种HIF-prolyl hydroxylase-2 (PHD-2) 抑制剂 |
808118-40-3 | IR0420 | Roxadustat;可博美 | C19H16N2O5 | 352.34 | HIF/HIF Prolyl-Hydroxylase | Roxadustat 是一种脯氨酰羟化酶 HIF 抑制剂。 |
38520-57-9 | IA4520 | N-Acetylcysteine Amide;N-乙酰-L-胱氨酸 | C5H10N2O2S | 162.21 | HIF-1α | 是一种抗氧化剂,具有消炎活性,能够调节NF-κB的激活、HIF-1α和ROS。 |
53123-88-9 | IR0010 | Rapamycin;雷帕霉素 | C51H79NO13 | 914.18 | mTOR | 是一种有效且特异性的mTOR 抑制剂和自噬激活剂。 |
38748-32-2 | IT0310 | Triptolide;雷公藤甲素 | C20H24O6 | 360.4 | NF-κB | 是 NF-κB 活化的抑制剂。 |
284461-73-0 | IS0220 | Sorafenib;索拉非尼 | C21H16ClF3N4O3 | 464.83 | Raf | 是Raf-1和B-Raf的多重激酶抑制剂,还可抑制VEGFR-2、VEGFR-3、PDGFR-β、Flt-3和c-KIT。 |
117-39-5 | IQ0010 | Quercetin;槲皮素 | C15H10O7 | 302.24 | PI3K | 是一种Sirt1激活剂同时也是PI3K抑制剂 |
35825-57-1 | IC0590 | Cryptotanshinone;隐丹参酮 | C19H20O3 | 296.36 | STAT | 是一种STAT3抑制剂 |
本套装精选了数种常用于细胞氧感应相关研究的化合物,便于客户进行初筛等操作。客户也可根据自己的需求灵活定制专属Kit。 |
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