CAS号 | 产品货号 | 产品名称 | 分子式 | 分子量 | 对应靶点 | 产品描述 |
27208-80-6 | IP0770 | Polydatin;虎杖苷 | C20H22O8 | 390.38 | ER Stress | 存在于传统中药虎杖根中,在多个实验模型中具有抗炎作用。据报道,可抑制G6PD,并诱导氧化和内质网应激 |
14605-22-2 | IT0790 | Tauroursodeoxycholic acid;牛磺熊去氧胆酸 | C26H45NO6S | 499.7 | ER Stress | 是一种内质网应激抑制剂。 |
35807-85-3 | IT0370 | Tauroursodeoxycholate Sodium;牛磺熊去氧胆酸钠 | C26H44NNaO6S | 521.69 | ER Stress,Caspase | 是一种内质网应激抑制剂,可显著降低凋亡分子如 caspase-3 和 caspase-12 表达。 |
1716-12-7 | IS0080 | Sodium 4-phenylbutyrate;4-苯基丁酸钠盐 | C10H11NaO2 | 186.18 | ER Stress | 是一种组蛋白去乙酰化酶 (HDAC) 和内质网应激 (ER) 抑制剂,可用于癌症和感染等疾病的研究。 |
73-31-4 | IM0080 | Melatonin;褪黑素 | C13H16N2O2 | 232.28 | ATF6 | 是一种激素,可激活褪黑激素受体。也是一种新型的选择性 ATF-6 抑制剂。 |
1589527-65-0 | IK0470 | KIRA6 | C28H25F3N6O | 518.53 | IRE1 | 是有效的II型IRE1α激酶抑制剂。 |
14003-96-4 | IM2400 | 8-Formyl-7-Hydroxy-4-Methyl-Coumarin;8-甲酰基-7-羟基-4-甲基香豆素 | C11H8O4 | 204.18 | IRE1 | 是高效的选择性IRE1 Rnase抑制剂。 |
307543-71-1 | IS1990 | STF083010 | C15H11NO3S2 | 317.38 | IRE1 | 是一种特异性IRE1α endonuclease抑制剂。 |
1337532-29-2 | IG1320 | GSK2656157 | C23H21FN6O | 416.45 | PERK | 是选择性,ATP竞争性的 PERK 抑制剂。 |
1337531-36-8 | IG1330 | GSK2606414 | C24H20F3N5O | 451.44 | PERK | 是PERK 抑制剂。 |
本套装精选了数种常用于内质网应激相关研究的化合物,便于客户进行初筛等操作。客户也可根据自己的需求灵活定制专属Kit。 |
Remark:
These protocols are for reference only. Solarbio does not independently validate these
methods.
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