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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Membrane Transporter & Ion Channel > A-803467CAS：944261-79-4
Molecular Formula：C19H16ClNO4
Molecular Weight：357.79
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 944261-79-4 |
| Name | A-803467 |
| Molecular Formula | C19H16ClNO4 |
| Molecular Weight | 357.79 |
| Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD01860946 |
| SMILES | O=C(C1=CC=C(C2=CC=C(Cl)C=C2)O1)NC3=CC(OC)=CC(OC)=C3 |
| Target Point | Sodium Channel |
| Passage | Membrane Transporter&Ion Channel |
| Background | A-803467 is a selective NaV1.8 channel inhibitor. |
| Biological Activity | A-803467是一种选择性NaV1.8 channel抑制剂，IC50为8 nM，抑制抗河豚毒的电流，比作用于人类NaV1.2， NaV1.3， NaV1.5和NaV1.7选择性高100倍以上。[1-2] |
| Data Literature Source | [1] Jarvis MF，et al. Proc Natl Acad Sci U S A，2007，104(20)，8520-8525. [2] Joshi SK，et al. J Pain，2009，10(3)，306-315. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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