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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > Aclidinium BromideCAS：320345-99-1
Molecular Formula：C26H30NO4S2·Br
Molecular Weight：564.55
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
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| CAS | 320345-99-1 |
| Name | Aclidinium Bromide |
| Molecular Formula | C26H30NO4S2·Br |
| Molecular Weight | 564.55 |
| Solubility | Soluble in DMSO ≥5mg/mL |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 825-171-6 |
| MDL | MFCD09954105 |
| SMILES | O=C(O[C@H]1C[N+]2(CCCOC3=CC=CC=C3)CCC1CC2)C(C4=CC=CS4)(O)C5=CC=CS5.[Br-] |
| Target Point | mAChR |
| Passage | Neuronal Signaling;GPCR & G Protein |
| Background | Aclidinium Bromide is a long-acting muscarinic antagonist that potently inhibits human muscarinic AChRs M1, M4, M3, and M5. |
| Biological Activity | Aclidinium Bromide (LAS 34273, LAS-W 330)与人源毒蕈碱受体AChR M1， M2， M3， M4和M5结合，Ki值分别为0.1 nM， 0.14 nM， 0.14 nM， 0.21 nM和0.16 nM。[1-3] |
| Data Literature Source | [1] Gavald A，et al. J Pharmacol Exp Ther，2009，331(2)，740-751. [2] Sentellas S，et al. Eur J Pharm Sci，2010，39(5)，283-290. [3] Milara J，et al. Thorax，2012，67(3)，229-237. |
| Unit | Bottle |
| Specification | 2mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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