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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Protein Tyrosine Kinase/PTK > AMG-337CAS：1173699-31-4
Molecular Formula：C23H22FN7O3
Molecular Weight：463.46
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1173699-31-4 |
| Name | AMG-337 |
| Molecular Formula | C23H22FN7O3 |
| Molecular Weight | 463.46 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | O=C1C2=C(N=CC(OCCOC)=C2)C=CN1[C@@H](C3=NN=C4C(F)=CC(C5=CN(C)N=C5)=CN43)C |
| Target Point | c-Met |
| Passage | Protein Tyrosine Kinase/RTK |
| Background | It is a potent and highly selective ATP-competitive MET kinase inhibitor. |
| Biological Activity | AMG 337是一种口服的、ATP竞争性的、高度选择性Met (c-Met) 受体抑制剂。IC50为1 nM。[1] |
| Data Literature Source | [1] Hughes PE，et al. Mol Cancer Ther. 2016，15(7):1568-1579. |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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