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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Protein Tyrosine Kinase/PTK > AP26113-AnalogCAS：1197958-12-5
Molecular Formula：C26H34ClN6O2P
Molecular Weight：529.01
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1197958-12-5 |
| Name | AP26113-Analog |
| Molecular Formula | C26H34ClN6O2P |
| Molecular Weight | 529.01 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 234-394-2 |
| MDL | MFCD23704187 |
| SMILES | CP(C)(C1=CC=CC=C1NC2=NC(NC3=CC=C(N4CCC(N(C)C)CC4)C=C3OC)=NC=C2Cl)=O |
| Target Point | ALK |
| Passage | Protein Tyrosine Kinase/RTK;Angiogenesis |
| Background | It is a potent and selective inhibitor of ALK kinase. |
| Biological Activity | AP26113-analog (ALK-IN-1) 是AP26113的类似物，是有效的、选择性的ALK抑制剂，同时也是EGFR的抑制剂。[1-2] |
| IC50 | ALK(Cell-free assay):0.07nM[1] |
| Data Literature Source | [1] Wei-Sheng Huang，et al. J Med Chem，2016，59(10):4948-4964. [2] Uchibori K，et al. Nat Commun. 2017，8:14768. |
| Unit | Bottle |
| Specification | 1mg 2mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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