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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Protein Tyrosine Kinase/PTK > AZ-191CAS：1594092-37-1
Molecular Formula：C24H27N7O
Molecular Weight：429.52
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Off-white to brown solid
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| CAS | 1594092-37-1 |
| Name | AZ-191 |
| Molecular Formula | C24H27N7O |
| Molecular Weight | 429.52 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Off-white to brown solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD28015098 |
| SMILES | CN1C2=CN=CC=C2C(C3=NC(NC4=CC=C(N5CCN(C)CC5)C=C4OC)=NC=C3)=C1 |
| Target Point | DYRK |
| Passage | Protein Tyrosine Kinase/RTK |
| Background | It is a potent and selective inhibitor of DYRK1B. |
| Biological Activity | AZ191是一种有效的选择性DYRK1B抑制剂，无细胞试验中IC50为17 nM，比作用于DYRK1A 和 DYRK2选择性分别高5和110倍。[1] |
| Data Literature Source | [1] Ashford AL，et al. Biochem J. 2014，457(1)，43-56. |
| Unit | Bottle |
| Specification | 2mg 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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