| Gene Name |
ATP6V0A2 |
| Synonyms |
a2;A2V ATPase;ARCL;ATP6a2;ATP6N1D;ATP6V0A2;ATPase，H+ transporting，lysosomal V0 subunit a isoform 2;ATPase，H+ transporting，lysosomal V0 subunit a2;Infantile malignant osteopetrosis;J6B7;Lysosomal H(+) transporting ATPase V0 subunit a2;Lysosomal H(+)-transporting ATPase V0 subunit a2;regeneration and tolerance factor;Stv1;TJ6;TJ6M;TJ6s;V ATPase 116 kDa isoform a2;V type proton ATPase 116 kDa subunit a;V type proton ATPase 116 kDa subunit a isoform 2;V-ATPase 116 kDa isoform a2;V-type proton ATPase 116 kDa subunit a isoform 2;Vacuolar proton translocating ATPase 116 kDa subunit a;Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2;Vph1;VPP2_HUMAN;WSS |
| English Name |
Recombinant human ATP6V0A2 protein |
| Full Name |
ATPase，H+ transporting，lysosomal V0 subunit a2 |
| Chinese Name |
V型质子ATP酶116 kDa亚基a2 |
| Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
| Purity |
≥85% by SDS-PAGE. |
| Storage |
Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
| Concentration |
1mg/ml by SDS-PAGE. |
| Swiss Prot |
Q9Y487 |
| Gene ID |
23545 |
| Reactivity |
Human Mouse (Bovine) |
| Molecular Weight |
40.6kDa |
| Interval Range |
50-400aa |
| Background |
Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633). |
| Application |
Immunology research |
| Source |
E.coli |
| Purification Method |
NI-NTA affinity purification |
| Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| Endotoxin |
Not measured |
| Biological Activity |
N0 |
| Lable Information |
With a 6×His tag at the N/C-terminus. |
| Unit |
Piece |
| Specification |
10ug 50ug 100ug 1mg |
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