| Gene Name |
GBA3 |
| Synonyms |
CBG;CBGL1;Cytosolic beta glucosidase;Cytosolic beta glucosidase like protein 1;Cytosolic beta-glucosidase;Cytosolic beta-glucosidase-like protein 1;GBA3;GBA3_HUMAN;GLUC;Glucosidase beta acid 3;Klotho related protein;KLRP |
| English Name |
Recombinant human GBA3 protein |
| Full Name |
glucosidase，beta，acid 3 (cytosolic) |
| Chinese Name |
胞浆β-葡萄糖苷酶 |
| Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
| Purity |
≥85% by SDS-PAGE. |
| Storage |
Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
| Concentration |
1mg/ml by SDS-PAGE. |
| Swiss Prot |
Q9H227 |
| Gene ID |
57733 |
| Reactivity |
Human (Orangutan) |
| Molecular Weight |
18kDa |
| Interval Range |
1-163aa |
| Background |
Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides (PubMed:11389701, PubMed:11784319, PubMed:20728381, PubMed:26724485, PubMed:17595169).Has a significant glucosylceramidase activity in vitro (PubMed:26724485, PubMed:17595169).However, that activity is relatively low and its significance in vivo is not clear (PubMed:26724485, PubMed:17595169, PubMed:20728381).Also able to hydrolyze galactosylceramide/GalCer, glucosylsphingosine/GlcSph and galactosylsphingosine/GalSph (PubMed:17595169).However, the in vivo relevance of these activities is unclear (PubMed:17595169).It can also hydrolyze a broad variety of dietary glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens in vitro and could therefore play a role in the metabolism of xenobiotics (PubMed:11784319).Could also play a role in the catabolism of cytosolic sialyl free N-glycans (PubMed:26193330). |
| Application |
Immunology research |
| Source |
E.coli |
| Purification Method |
NI-NTA affinity purification |
| Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| Endotoxin |
Not measured |
| Biological Activity |
N0 |
| Lable Information |
With a 6×His tag at the N/C-terminus. |
| Unit |
Piece |
| Specification |
10ug 50ug 100ug 1mg |
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