Gene Name |
BMPR2 |
Synonyms |
BMP type II receptor;BMP type-2 receptor;BMPR 2;BMPR 3;BMPR II;BMPR-2;BMPR-II;Bmpr2;BMPR2_HUMAN;BMPR3;BMPRII;BMR 2;BMR2;Bone morphogenetic protein receptor type 2;Bone morphogenetic protein receptor type II;Bone morphogenetic protein receptor type-2;Bone morphogenic protein receptor type II serine threonine kinase;BRK 3;BRK3;PPH 1;PPH1;Serine threonine kinase type II activin receptor like kinase;T ALK;TALK;Type II activin receptor like kinase |
English Name |
Recombinant human BMPR2 protein |
Full Name |
bone morphogenetic protein receptor,type II (serine/threonine kinase) |
Chinese Name |
骨形态发生蛋白受体-2型 |
Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Purity |
≥85% by SDS-PAGE. |
Storage |
Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year. |
Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
Concentration |
1mg/ml by SDS-PAGE. |
Swiss Prot |
Q13873 |
Gene ID |
659 |
Reactivity |
Human Mouse |
Molecular Weight |
38kDa |
Interval Range |
600-950aa |
Background |
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6. |
Application |
Immunology research |
Source |
E.coli |
Purification Method |
NI-NTA affinity purification |
Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
Endotoxin |
Not measured |
Biological Activity |
N0 |
Lable Information |
With a 6×His tag at the N/C-terminus. |
Unit |
Piece |
Specification |
10ug 50ug 100ug 1mg |