| Gene Name |
HEXB |
| Synonyms |
ENC-1AS;HEL-248;HEL-S-111；Beta hexosaminidase beta chain;Beta hexosaminidase subunit beta;Beta N acetylhexosaminidase;Beta-hexosaminidase subunit beta chain A;Beta-N-acetylhexosaminidase subunit beta;Cervical cancer proto oncogene 7 protein;Cervical cancer proto-oncogene 7 protein;ENC 1AS;Epididymis luminal protein 248;HCC 7;HCC-7;HCC7;HEL 248;HEX B;Hexb;HEXB_HUMAN;Hexosaminidase B (beta polypeptide);Hexosaminidase B;Hexosaminidase subunit B;HexosaminidaseB;N acetyl beta glucosaminidase;N-acetyl-beta-glucosaminidase subunit beta |
| English Name |
Recombinant human HEXB protein |
| Full Name |
hexosaminidase B (beta polypeptide) |
| Chinese Name |
己糖胺酶B, β多肽 |
| Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
| Purity |
≥85% by SDS-PAGE. |
| Storage |
Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
| Concentration |
1mg/ml by SDS-PAGE. |
| Swiss Prot |
P07686 |
| Gene ID |
3074 |
| Reactivity |
Human Mouse Rat (Pig Cat) |
| Molecular Weight |
38kDa |
| Interval Range |
207-557aa |
| Background |
Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A. During fertilization is responsible, at least in part, for the zona block to polyspermy. Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and inactivates the sperm galactosyltransferase-binding site, accounting for the block in sperm binding to the zona pellucida (By similarity). |
| Application |
Immunology research |
| Source |
E.coli |
| Purification Method |
NI-NTA affinity purification |
| Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| Endotoxin |
Not measured |
| Biological Activity |
N0 |
| Lable Information |
With a 6×His tag at the N/C-terminus. |
| Unit |
Piece |
| Specification |
10ug 50ug 100ug 1mg |
English
中文
Manual Download
