Gene Name |
UBASH3B |
Synonyms |
STS-1;STS1;TULA-2;TULA2;p70;Cbl interacting protein p70;Cbl interacting protein Sts 1;Cbl interacting protein Sts1;Cbl-interacting protein p70;KIAA1959;MGC15437;Nm23 phosphorylated unknown substrate;p70;SH3 domain containing 70 kDa protein;Sts 1;STS-1;STS1;Suppressor of T cell receptor signaling 1;Suppressor of T-cell receptor signaling 1;T-cell ubiquitin ligand 2;TULA-2;Tyrosine-protein phosphatase STS1/TULA2;Ubash3b;Ubiquitin associated and SH3 domain containing B;Ubiquitin-associated and SH3 domain-containing protein B;UBS3B_HUMAN |
English Name |
Recombinant human UBASH3B protein |
Full Name |
ubiquitin associated and SH3 domain containing,B |
Chinese Name |
泛素相关包含SH3结构域蛋白B |
Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Purity |
≥85% by SDS-PAGE. |
Storage |
Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year. |
Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
Concentration |
1mg/ml by SDS-PAGE. |
Swiss Prot |
Q8TF42 |
Gene ID |
84959 |
Reactivity |
Human Mouse |
Molecular Weight |
39kDa |
Interval Range |
1-350aa |
Background |
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination. |
Application |
Immunology research |
Source |
E.coli |
Purification Method |
NI-NTA affinity purification |
Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
Endotoxin |
Not measured |
Biological Activity |
N0 |
Lable Information |
With a 6×His tag at the N/C-terminus. |
Unit |
Piece |
Specification |
10ug 50ug 100ug 1mg |