Gene Name |
DLC1 |
Synonyms |
ARHGAP7;HP;STARD12;p122-RhoGAP;ARHGAP 7;ARHGAP7;Deleted in liver cancer 1;Deleted in liver cancer 1 protein;DLC 1;Dlc-1;DLC1;DLC1 Rho GTPase activating protein;FLJ21120;HP;HP protein;KIAA1723;p122 RhoGAP;RHG07_HUMAN;Rho GTPase activating protein 7;Rho GTPase-activating protein 7;Rho type GTPase activating protein 7;Rho-type GTPase-activating protein 7;StAR related lipid transfer (START) domain containing 12;StAR related lipid transfer protein 12;StAR-related lipid transfer protein 12;STARD 12;StARD12;START domain containing protein 12;START domain-containing protein 12 |
English Name |
Recombinant human DLC1 protein |
Full Name |
deleted in liver cancer 1 |
Chinese Name |
肝癌缺失基因1 |
Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Purity |
≥85% by SDS-PAGE. |
Storage |
Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year. |
Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
Concentration |
1mg/ml by SDS-PAGE. |
Swiss Prot |
Q96QB1 |
Gene ID |
10395 |
Reactivity |
Human Mouse Rat (Bovine Rabbit Dog) |
Molecular Weight |
39kDa |
Interval Range |
1-350aa |
Background |
Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality. |
Application |
Immunology research |
Source |
E.coli |
Purification Method |
NI-NTA affinity purification |
Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
Endotoxin |
Not measured |
Biological Activity |
N0 |
Lable Information |
With a 6×His tag at the N/C-terminus. |
Unit |
Piece |
Specification |
10ug 50ug 100ug 1mg |