Gene Name |
PPP2R2D |
Synonyms |
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform;PP2A subunit B isoform B55-delta;PP2A subunit B isoform PR55-delta;PP2A subunit B isoform R2-delta;PP2A subunit B isoform delta;KIAA1541;2ABD_HUMAN;MDS026;Protein phosphatase 2 regulatory subunit B delta;Protein phosphatase 2 regulatory subunit B delta isoform |
English Name |
Recombinant human PPP2R2D protein |
Full Name |
protein phosphatase 2,regulatory subunit B,delta isoform |
Chinese Name |
蛋白磷酸酶2调节亚基Bδ |
Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Purity |
≥85% by SDS-PAGE. |
Storage |
Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year. |
Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
Concentration |
1mg/ml by SDS-PAGE. |
Swiss Prot |
Q66LE6 |
Gene ID |
55844 |
Reactivity |
Human Mouse Rat (ZebraFish) |
Molecular Weight |
40kDa |
Interval Range |
1-350aa |
Background |
B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). |
Application |
Immunology research |
Source |
E.coli |
Purification Method |
NI-NTA affinity purification |
Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
Endotoxin |
Not measured |
Biological Activity |
N0 |
Lable Information |
With a 6×His tag at the N/C-terminus. |
Unit |
Piece |
Specification |
10ug 50ug 100ug 1mg |