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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > PI3K/Akt/mTOR > Bempedoic AcidCAS：738606-46-7
Molecular Formula：C19H36O5
Molecular Weight：344.49
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to yellow Solid
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| CAS | 738606-46-7 |
| Name | Bempedoic Acid |
| Molecular Formula | C19H36O5 |
| Molecular Weight | 344.49 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | CC(C)(CCCCCC(CCCCCC(C)(C)C(=O)O)O)C(=O)O |
| Target Point | ATPCitrate Lyase (ACL)，AMPK |
| Passage | PI3K/Akt/mTOR;Epigenetics |
| Background | Bempedoic Acid is an ATP-citrate lyase (ACL) inhibitor that activates AMPK. |
| Biological Activity | Bempedoic acid (ETC-1002) is an ATP-citrate lyase (ACL) inhibitor[1]. Bempedoic acid (ETC-1002) activates AMPK[2]. |
| IC50 | AMPK |
| Data Literature Source | [1]. Pinkosky SL，et al. AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002，a novel small molecule regulator of lipid and carbohydrate metabolism. J Lipid Res. 2013 Jan;54(1):134-51. [2]. Filippov S，et al. ETC-1002 regulates immune response，leukocyte homing，and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK. J Lipid Res. 2013 Aug;54(8):2095-108. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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