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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > DNA Damage & DNA Repai > BufexamacCAS：2438-72-4
Molecular Formula：C12H17NO3
Molecular Weight：223.27
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 2438-72-4 |
| Name | Bufexamac |
| Molecular Formula | C12H17NO3 |
| Molecular Weight | 223.27 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 219-451-1 |
| MDL | MFCD00078936 |
| SMILES | O=C(NO)CC1=CC=C(OCCCC)C=C1 |
| InChIKey | MXJWRABVEGLYDG-UHFFFAOYSA-N |
| InChI | InChI=1S/C12H17NO3/c1-2-3-8-16-11-6-4-10(5-7-11)9-12(14)13-15/h4-7,15H,2-3,8-9H2,1H3,(H,13,14) |
| PubChem CID | 2466 |
| Target Point | HDAC，IFN-α，COX |
| Passage | DNA Damage/DNA Repair;Epigenetics;NF-κB |
| Background | It is an inhibitor of HDAC6 and HDAC10 with anti-inflammatory activity; it is also a COX inhibitor that targets IFN-α. |
| Data Literature Source | [1]. Bantscheff，M.，et al.，Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes. Nat Biotechnol，2011. 29(3): p. 255-65. [2]. Kranke，B.，et al.，Epidemiological significance of bufexamac as a frequent and relevant contact sensitizer. Contact Dermatitis，1997. 36(4): p. 212-5. |
| Unit | Bottle |
| Specification | 25mg 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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