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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Angiogenesis > Cediranib MaleateCAS：857036-77-2
Molecular Formula：C25H27FN4O3·C4H4O4
Molecular Weight：566.58
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 857036-77-2 |
| Name | Cediranib Maleate |
| Molecular Formula | C25H27FN4O3·C4H4O4 |
| Molecular Weight | 566.58 |
| Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | O=C(O)/C=C\C(O)=O.FC1=C(OC2=C(C(C=C3OCCCN4CCCC4)=NC=N2)C=C3OC)C=CC5=C1C=C(C)N5 |
| Target Point | VEGFR |
| Passage | Angiogenesis;Protein Tyrosine Kinase/RTK |
| Background | It is a highly selective VEGFR2 inhibitor. |
| Biological Activity | Cediranib maleate (AZD-2171 maleate) is a highly potent， orally available VEGFR inhibitor with IC50s of PDGFRα， PDGFRβ， c-Kit， respectively.[1] |
| Data Literature Source | [1]. Wedge SR， et al. AZD2171: a highly potent， orally bioavailable， vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer. Cancer Res， 2005， 65(10)， 4389-4400. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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